Clinical medicine profile
Torasemide or Torsemide
Therapeutic agent (verify pharmacological class)
- Route
- See product SmPC
- Schedule
- POM
- ATC
- Not assigned
- PPB status
- registered
This profile needs source confirmation
Some sections contain general class guidance rather than medicine-specific evidence. Confirm prescribing decisions against the current SmPC and Kenya STG/EML.
Safety essentials
The information most likely to change a prescribing or dispensing decision.
Contraindications
- Hypersensitivity to the active substance or excipients.
- Additional absolute contraindications are indication- and product-specific — consult SmPC.
Precautions
- Pregnancy and lactation, impaired hepatic or / and renal functions, diabetes mellitus, gout, potassium depleting, steroid therapy.
- Precaution in Hepatic Diseases: Reduce the dose in case of impaired hepatic function
- Precautions in renal Diseases: No dose adjustment is required.
Dosing matrix
Population and organ-function guidance, shown together for faster comparison.
Dosing is indication-, age-, weight- and organ-function-specific for this INN. Do not use class averages for high-risk patients. Confirm the exact regimen in the current SmPC and Kenya Standard Treatment Guidelines. Typical professional workflow: (1) confirm indication, (2) check renal/hepatic function, (3) screen interactions/allergies, (4) select dose/route/duration, (5) define monitoring.
Paediatric dosing is weight- and age-based; use a paediatric formulary / SmPC. Do not extrapolate adult tablets without calculation.
Review renal impairment dosing; many agents need CrCl/eGFR adjustment.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Review hepatic impairment dosing; monitor LFTs if agent is hepatically cleared or hepatotoxic.
Use, effects & interactions
Indications
- Oedema, oliguria due to renal failure, mild to moderate hypertension, barbiturate poisoning.
- Clinical selection for Torasemide or Torsemide should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC.
- Class context: Therapeutic agent (verify pharmacological class).
- Confirm site-specific dose, duration and monitoring before prescribing.
Adverse effects
- GI disturbances, headache, fatigue, dizziness, blood dyscrasia, orthostatic hypotension, allergic reactions, hypokaleamia, hypomagnesia, hyponatreamia, hyperglycaemia, tinnitus, and deafness.
Drug interactions
Open multi-drug checker ↗- Compared to furosemide and other loop diuretics, it has a longer diuretic effect than equal doses of furosemide.
- It causes less potassium-loss effect and practically no ototoxic side effect.
Mechanism & disposition
Inhibits re-absorption of sodium and chloride in proximal and distal tubules and at the loop of henle.
Read complete mechanism
Inhibits re-absorption of sodium and chloride in proximal and distal tubules and at the loop of henle. Mechanism is agent-specific. At receptor, enzyme, ion channel, transporter or microbial target level, the drug alters a physiological or pathological pathway to produce its therapeutic effect. Confirm precise molecular mechanism in current SmPC / pharmacology reference for this INN before high-stakes decisions.
Product-specific
Product-specific
See product SmPC
are product-specific. Consider food effects, protein binding, hepatic CYP/UGT
when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC.
Pregnancy, lactation & diet
Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.
Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.
Brands & loaded prices
| Brand | Manufacturer | Pack | Observed price |
|---|---|---|---|
| DIURIDE | DAIMA BIASHARA / Wholesale Import | 10MG 20`S | KES 1,607.34Daima Chemist price-list reference ↗ Source date not recorded · verify current price |
| TIBINA 10MG TABLETS | COSMOS LIMITED | Tablet 10MG | Unavailable |
| TIBINA 20MG TABLETS | COSMOS LIMITED | Tablet 20MG | Unavailable |
| TORAS DENK | DAIMA BIASHARA / Wholesale Import | 10MG 30*S | KES 1,365.10Daima Chemist price-list reference ↗ Source date not recorded · verify current price |
| TORSINEX | DAIMA BIASHARA / Wholesale Import | 10MG TABS 30`S | KES 1,128.75daima_biashara_price_list |
| Torsinex 10 Tablets | Micro Labs Limited | Tablet | Unavailable |
Sources & review state
Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.