Clinical medicine profile
Clindamycin
Therapeutic agent (verify pharmacological class)
- Route
- See product SmPC
- Schedule
- POM
- ATC
- Not assigned
- PPB status
- registered
This profile needs source confirmation
Some sections contain general class guidance rather than medicine-specific evidence. Confirm prescribing decisions against the current SmPC and Kenya STG/EML.
Safety essentials
The information most likely to change a prescribing or dispensing decision.
Contraindications
- Hypersensitivity to the active substance or excipients.
- Additional absolute contraindications are indication- and product-specific — consult SmPC.
Precautions
- Obtain allergy and medication history.
- Adjust for renal/hepatic impairment, pregnancy, lactation, extremes of age and interacting drugs.
- Use the lowest effective dose for the shortest appropriate duration.
- Monitor for expected class adverse effects.
Dosing matrix
Population and organ-function guidance, shown together for faster comparison.
Dosing is indication-, age-, weight- and organ-function-specific for this INN. Do not use class averages for high-risk patients. Confirm the exact regimen in the current SmPC and Kenya Standard Treatment Guidelines. Typical professional workflow: (1) confirm indication, (2) check renal/hepatic function, (3) screen interactions/allergies, (4) select dose/route/duration, (5) define monitoring.
Paediatric dosing is weight- and age-based; use a paediatric formulary / SmPC. Do not extrapolate adult tablets without calculation.
Review renal impairment dosing; many agents need CrCl/eGFR adjustment.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Review hepatic impairment dosing; monitor LFTs if agent is hepatically cleared or hepatotoxic.
Use, effects & interactions
Indications
- Mild to moderate acne vulgaris
- minor bacterial skin infections.
- Clinical selection for Clindamycin (topical) should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC.
- Class context: Therapeutic agent (verify pharmacological class).
- Confirm site-specific dose, duration and monitoring before prescribing.
Adverse effects
- Adverse reactions vary by agent.
- Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
- Report suspected ADRs via national pharmacovigilance channels.
Drug interactions
Open multi-drug checker ↗- Professional use: confirm indication, dose, duration, monitoring and patient counselling points against current Kenya STG / EML and the product SmPC.
- Document allergy status and key interactions.
Mechanism & disposition
Inhibits growth of Propionibacterium acnes.
Read complete mechanism
Inhibits growth of Propionibacterium acnes. Mechanism is agent-specific. At receptor, enzyme, ion channel, transporter or microbial target level, the drug alters a physiological or pathological pathway to produce its therapeutic effect. Confirm precise molecular mechanism in current SmPC / pharmacology reference for this INN before high-stakes decisions.
Product-specific
Product-specific
See product SmPC
are product-specific. Consider food effects, protein binding, hepatic CYP/UGT
when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC.
Pregnancy, lactation & diet
Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.
Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.
Brands & loaded prices
| Brand | Manufacturer | Pack | Observed price |
|---|---|---|---|
| ClindarGelWallae1% | Afya Index / Retail Reference | Kenyaliq 5% 5L | KES 1,008,000.00afya_index_book |
| CLINDAZEN 150 | ZAIN PHARMA LIMITED | Hard Gelatin Capsules | Unavailable |
| CLINDAZEN 300 | ZAIN PHARMA LIMITED | Hard Gelatin Capsules | Unavailable |
| CLINEP | NESHER PHARMA LD | Injection | Unavailable |
| DALACIN C | DAIMA BIASHARA / Wholesale Import | CAPS 300MG 16`s | KES 1,869.02daima_biashara_price_list |
| Dalacin C 150mg | Pfizer Laboratories Limited | Capsule 150mg | Unavailable |
| Dalacin C 300mg | Pfizer Laboratories Limited | Capsule 300mg | Unavailable |
| Dalacin C injection | Pfizer Laboratories Limited | Solution For Injection | Unavailable |
| Monotax? | Afya Index / Retail Reference | tabs 1's | KES 102.00afya_index_book |
| PIP-OFF GEL | Bliss GVS Pharma Ltd. | Gel | Unavailable |
| PIP OFF | DAIMA BIASHARA / Wholesale Import | GEL 25GM | KES 322.94daima_biashara_price_list |
| Powercef | Afya Index / Retail Reference | tabs 1g 1's | KES 350.00afya_index_book |
| Powercef? | Afya Index / Retail Reference | tabs 1g 1's | KES 350.00afya_index_book |
Sources & review state
Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.