AfyaIndex — Drug Search

01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Critical warning

WARNING Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF THE REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.

Contraindications

Hypervitaminosis risk states (hypercalcaemia for vitamin D/A).
Iron: avoid in iron overload.
Potassium: severe hyperkalaemia / untreated Addison's.

Precautions

WARNING Ingestion of more than 3 grams of omega-3 fatty acids per day has been shown to have potential antithrombotic effects, including an increased bleeding time and INR.
Administration of omega-3 fatty acids should be avoided in patients on anticoagulants and in those known to have an inherited or acquired bleeding diathesis.
WARNING Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B 12 is deficient.

02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

DOSAGE AND ADMINISTRATION One tablet and one capsule daily or as directed by a physician.

Paediatric

See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.

Renal

Fat-soluble vitamins and potassium need care in advanced CKD.

CrCl 0–120: Confirm renal dosing in product SmPC / primary label.

Hepatic

Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.

03 Clinical use

Use, effects & interactions

Indications

INDICATIONS CitraNatal Assure ® is a multivitamin/mineral prescription drug indicated for use in improving the nutritional status of women prior to conception, throughout pregnancy, and in the postnatal period for both lactating and nonlactating mothers.

Adverse effects

GI upset (iron, high-dose vitamin C).
Hypercalcaemia (vitamin D excess).
Neuropathy with B6 megadoses.
Flushing (niacin).

Drug interactions

Open multi-drug checker ↗

Prefer food-first then targeted replacement.
Document laboratory indication for high-dose therapy.
Public health: vitamin A, iron, folate programmes per MoH guidance.

04 Pharmacology

Mechanism & disposition

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.

Vitamins and minerals act as cofactors, an…Pharmacological high-dose effects differ f…

Read complete mechanism

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.g. vitamin D endocrine axis). Pharmacological high-dose effects differ from nutritional repletion.

Onset

Days–weeks for repletion

Duration

Depends on stores and ongoing intake

Route

ORAL / IM / IV (selected)

Absorption

depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

Folic acid preconception/first trimester critical. Iron/folate common in ANC. Avoid excess vitamin A.

Lactation

Maternal repletion often appropriate; avoid megadoses.

06 Kenya market

Brands & loaded prices

From—

Median—

Listings0

Brand	Manufacturer	Pack	Observed price
No reviewed brand listings are linked yet.

07 Provenance

Sources & review state

Primary sourceFDA drug label via OpenFDA/DailyMed; Local active-ingredient clinical extract; Professional class pharmacology (Vitamin / mineral / nutritional supplement)

Last reviewedNot recorded

EvidenceSource-linked

Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.