Miconazole/ Hydrocortisone

[Miconazole] [From component Triamcinolone acetonide] PREGNANCY CATEGORY C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time. [Hydrocortisone] Used when maternal benefit clear; prefer agents with better obstetric data (e.g. prednisolone). Document risk–benefit.

[Miconazole] [From component Triamcinolone acetonide] NURSING MOTHERS It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman. [Hydrocortisone] Low-dose systemic often compatible; time feeds if high dose — agent-specific.