Clinical medicine profile
Measles Vaccine
Vaccine / immunological product
- Route
- IM / SC / ORAL / ID
- Schedule
- POM
- ATC
- Not assigned
- PPB status
- registered
This profile needs source confirmation
A traceable source link is not attached to this profile. Confirm prescribing decisions against the current SmPC and Kenya STG/EML.
Safety essentials
The information most likely to change a prescribing or dispensing decision.
Contraindications
- Anaphylaxis to prior dose or component.
- Live vaccines contraindicated in significant immunosuppression and usually pregnancy.
- Defer for moderate–severe acute illness.
Precautions
- Observe 15 minutes post-dose if high anaphylaxis concern.
- Correct injection technique and site.
- Report AEFI via national systems.
Dosing matrix
Population and organ-function guidance, shown together for faster comparison.
Dosing is indication-, age-, weight- and organ-function-specific for this INN. Do not use class averages for high-risk patients. Confirm the exact regimen in the current SmPC and Kenya Standard Treatment Guidelines. Typical professional workflow: (1) confirm indication, (2) check renal/hepatic function, (3) screen interactions/allergies, (4) select dose/route/duration, (5) define monitoring.
Paediatric dosing is weight- and age-based; use a paediatric formulary / SmPC. Do not extrapolate adult tablets without calculation.
N/A generally.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
N/A generally.
Use, effects & interactions
Indications
- Therapeutic use is agent- and indication-specific within the class (Vaccine / immunological product).
- Use according to culture results, national guidelines (Kenya STG/EML where applicable) and the current product SmPC.
- Active immunization against measles.
Adverse effects
- Local pain, low-grade fever, myalgia.
- Serious: anaphylaxis, vaccine-specific rare events (e.g. intussusception historically with some rotavirus products).
Drug interactions
Open multi-drug checker ↗- Follow Kenya KEPI / MoH schedules.
- Never freeze freeze-sensitive vaccines incorrectly.
- Document batch and site.
- Separate true contraindications from precautions.
Mechanism & disposition
Stimulates immune system to produce antibodies corresponding to the vaccine antigen Vaccines present antigen to the adaptive immune system to generate protective antibodies and memory cells without causing full disease (or using attenuated/inactivated/subunit/mRNA platforms).
Read complete mechanism
Stimulates immune system to produce antibodies corresponding to the vaccine antigen Vaccines present antigen to the adaptive immune system to generate protective antibodies and memory cells without causing full disease (or using attenuated/inactivated/subunit/mRNA platforms). Immunoglobulins provide passive temporary immunity.
Immune response days–weeks
Months–lifelong (schedule-dependent)
IM / SC / ORAL / ID
Pregnancy, lactation & diet
Inactivated vaccines (e.g. influenza, Tdap) often recommended; live vaccines generally avoided.
Most vaccines compatible; live vaccines usually fine for breastfeeding mother.
Brands & loaded prices
| Brand | Manufacturer | Pack | Observed price |
|---|---|---|---|
| No reviewed brand listings are linked yet. | |||
Sources & review state
Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.