Erythromycin+ Zinc acenate Lotion
Macrolide [EPC], Macrolide Antimicrobial [EPC]
What it is used for
INDICATIONS AND USAGE Erythromycin Topical Solution USP, 2% is indicated for the topical treatment of acne vulgaris. Clinical selection for Erythromycin+ Zinc acenate Lotion should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC. Class context: Macrolide [EPC], Macrolide Antimicrobial [EPC]. Confirm site-specific dose, duration and monitoring before prescribing.
Warnings
WARNINGS Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is one primary cause of “antibiotic-associated colitis”. After the diagnosis of pseudomembranous colitis has been established, therapeutic measures should be initiated. Mild cases of pseudomembranous colitis usually respond to drug discontinuation alone. In moderate to severe cases, consideration should be given to management with fluids and electrolytes, protein supplementation and treatment with an antibacterial drug clinically effective against C. difficile colitis.
Possible side effects
ADVERSE REACTIONS The following local adverse reactions have been reported occasionally: peeling, dryness, itching, erythema, and oiliness. Irritation of the eyes and tenderness of the skin have also been reported with topical use of erythromycin. Generalized urticarial reactions possibly related to the use of erythromycin, which required systemic steroid therapy have been reported.
Storage
HOW SUPPLIED Erythromycin Topical Solution USP, 2% is available as follows: 60 mL bottle with applicator (NDC 72162-2075-6) Repackaged/Relabeled by: Bryant Ranch Prepack, Inc. Burbank, CA 91504
No reviewed patient-education article is available. The fields shown are from the currently verified medicine record and unavailable fields are not inferred.