Cefotaxime
Beta-lactam antibiotic — cephalosporin
What it is used for
Septicaemia, meningitis in neonates and infants, peri-operative infections prophylaxis, UTI, RTI, bone, joints, skin and soft tissue infections. Clinical selection for Cefotaxime should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC. Class context: Beta-lactam antibiotic — cephalosporin. Confirm site-specific dose, duration and monitoring before prescribing.
Warnings
Allergy history. Superinfection / C. difficile risk. Adjust renally cleared agents for CrCl. Ceftriaxone: avoid concurrent IV calcium in neonates; biliary sludge with prolonged use.
Possible side effects
GI disturbances, allergic reactions, blood dyscrasia, severe headaches, glossitis, pain at I.M injection site, pseudomembranous entero-colitis, oedema, genital tract mycosis, oliguria.
Storage
Store as labelled. Keep out of reach of children.
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