Methotrexate
Therapeutic agent (verify pharmacological class)
What it is used for
Gestational choriocarcinoma, chorioadenoma destruens; hydatidiform mole; acute lymphocytic leukemia; meningeal leukemia; breast cancer; epidermoid cancers of the head and neck; advanced mycosis fungoides; lung cancer, particularly squamous cell and small cell types; non-Hodgkin's lymphomas; non-metastatic osteosarcoma; severe, recalcitrant, disabling psoriasis; severe, active, classical or definite rheumatoid arthritis unresponsive to conventional therapy.
Warnings
Should be used in the treatment of neoplastic diseases in pregnancy only when the potential benefit outweighs the risk to the fetus; pregnancy should be avoided if either partner is on the drug. 8, 10a, 20
Possible side effects
Ulcerative stomatitis; leukopenia; nausea; anorexia; vomiting; abdominal distress; malaise; asthenia; chills and fever; dizziness; decreased resistance to infection; gingivitis; pharyngitis; diarrhoea; hematemesis; melena; GI ulceration and bleeding; enteritis; transient subtle cognitive dysfunction; mood alteration; unusual cranial sensations; headache; drowsiness; blurred vision; interstitial pneumonitis; erythematous rashes, pruritus; urticaria; photosensitivity; pigmentary changes; alopecia; ecchymosis; telangiectasia; acne; furunculosis.
Storage
Store as labelled. Keep out of reach of children.
No reviewed patient-education article is available. The fields shown are from the currently verified medicine record and unavailable fields are not inferred.